材料科学
自愈
伤口愈合
背景(考古学)
伤口护理
生物医学工程
拉伤
纳米技术
复合材料
医学
外科
生物
古生物学
替代医学
病理
内科学
作者
Yanni Bi,Mimi Sun,Yuanyuan Zhang,Fuxin Sun,Yan Du,Jingjuan Wang,Ming Zhou,C Ma
标识
DOI:10.1002/adhm.202302810
摘要
Effective wound healing is critical for patient care, and the development of novel wound dressing materials that promote healing, prevent infection, and are user-friendly is of great importance, particularly in the context of point-of-care testing (POCT). This study reports the synthesis of a hydrogel material that can be produced in less than 10 s and possesses antibacterial activity against both gram-negative and gram-positive microorganisms, as well as the ability to inhibit the growth of eukaryotic cells, such as yeast. The hydrogel is formed wholly based on covalent-like hydrogen bonding interactions and exhibits excellent mechanical properties, with the ability to stretch up to more than 600% of its initial length. Furthermore, the hydrogel demonstrates ultra-fast self-healing properties, with fractures capable of being repaired within 10 s. This hydrogel can promote skin wound healing, with the added advantage of functioning as a strain sensor that generates an electrical signal in response to physical deformation. The strain sensor composed of a rubber shell realizes fast and responsive strain sensing. The findings suggest that this hydrogel has promising applications in the field of POCT for wound care, providing a new avenue for improved patient outcomes.
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