Advancements in Portable Electrospinning Technology for Wound Healing Applications: A Comprehensive Review

Portable electrospinning technology has recently made significant advancements, offering promising applications for wound healing. These devices enable the in situ fabrication of nanofiber dressings directly onto wound sites, providing personalised and efficient treatment. Portable electrospinning devices can be categorised into handheld spinnerets, battery-powered systems, and generator-powered setups, each with distinct advantages and limitations. Handheld devices offer high portability for precise, small-scale applications, whilst battery-powered systems balance portability and operational duration. Generator-powered setups provide a consistent power supply to improve fibre quality. Recent studies have demonstrated the efficacy of portable electrospinning devices in producing antibacterial membranes, hydrogel-forming dressings, and accelerating wound closure. However, challenges persist in achieving consistent fibre deposition, adjustable voltages, and controlled delivery. Developing portable electrospinning devices requires interdisciplinary collaboration and careful consideration of safety measures, usability, and rapid prototyping. Despite these challenges, the potential of portable electrospinning technology for emergency wound treatment and personalised care is significant, particularly for complex conditions, such as epidermolysis bullosa. Further research and refinement are warranted to address these challenges and optimise portable electrospinning devices for clinical applications.