Adherence to Hypertension Medication in Older People: Empirical Research Quantitative

医学 药物依从性 逻辑回归 优势比 置信区间 横断面研究 匹兹堡睡眠质量指数 多元分析 生活质量(医疗保健) 内科学 老年学 睡眠质量 精神科 病理 护理部 认知
作者
Mengyun Huang,Li-jun Zhu,Yan Chen,Anshi Wang,Jing Wang,Wenjuan Zhang,Yang Wang,Yuelong Jin,Yingshui Yao
出处
期刊:Current Vascular Pharmacology [Bentham Science Publishers]
卷期号:23 (4): 289-300
标识
DOI:10.2174/0115701611298963241218113618
摘要

Introduction: This study aimed to investigate the factors influencing medication adherence in community-dwelling Chinese older adults with hypertension. Design: Empirical research–quantitative; Cross-sectional study. Methods: A cross-sectional survey was conducted from September to December 2021, in which participants completed a self-administered questionnaire with detailed their demographic information. The Morisky Medication Adherence Scale-8, the Pittsburgh Sleep Quality Index, and the 10-item Kessler Psychological Distress Scale were used to assess medication adherence, sleep quality, and psychological well-being, respectively. Multivariate logistic regression analysis was performed with medication adherence as the dependent variable to identify factors influencing adherence. Results: The study included 867 patients with hypertension, comprising 566 women and 301 men with a mean age of 70.89 ± 7.50 years. Results indicated that 53.9% of participants exhibited high medication adherence, while 24.5% and 21.7% demonstrated medium and low adherence levels, respectively. Multiple logistic regression analysis revealed that individuals in the 50–59 age group had lower medication adherence compared to those aged 80 years and older (odds ratio [OR]: 0.468, 95% confidence interval [CI]: 0.245,0.894). In addition, participants with a primary school education or less (OR: 0.152, 95% CI: 0.095,0.245) and those living alone (OR: 0.362, 95% CI: 0.228, 0.575) exhibited poorer medication adherence. Conversely, living in an urban area was associated with better adherence (OR: 2.131, 95% CI: 1.402, 3.239, p < 0.001). Conclusion: Our study showed that participants' medication adherence was below the desired level. It was observed that older adults, those with a junior high school education or higher, and those living in urban areas with their children had better medication adherence. These identified predictors may help to identify individuals at high risk of poor adherence, enabling the implementation of effective interventions to reduce the global burden of hypertension.
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