Restless Legs and Iron Deficiency: Unraveling the Hidden Link and Unlocking Relief

Restless legs syndrome (RLS), also called Willis-Ekbom disease (WED), is a condition marked by an overwhelming urge to move the legs, particularly during rest or at night. Treatments, including intravenous iron, show potential, but further studies are needed to establish their long-term safety and efficacy. The findings integrate various studies to better understand diagnosis, mechanisms, and treatment options for RLS. This review explores the connection between RLS and iron deficiency, emphasizing iron metabolism and its potential role in disease development.