淋巴瘤
汽车T细胞治疗
医学
癌症研究
肿瘤科
内科学
免疫疗法
癌症
嵌合抗原受体
作者
Jakub Svoboda,Daniel J. Landsburg,James N. Gerson,Sunita D. Nasta,Stefan K. Barta,Elise A. Chong,Michael Cook,Noelle V. Frey,Joanne Shea,Amanda Cervini,Amy Marshall,Megan Four,Megan M. Davis,Julie K. Jadlowsky,Anne Chew,Edward Pequignot,Vanessa Gonzalez,Julia Han Noll,Luca Paruzzo,Juliana Rojas-Levine
标识
DOI:10.1056/nejmoa2408771
摘要
In this small study, huCART19-IL18 had a safety profile consistent with other CAR T-cell treatments and showed promising efficacy at low cell doses in patients with lymphoma after the failure of previous anti-CD19 CAR T-cell therapy. (ClinicalTrials.gov number, NCT04684563.).
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