The extraction of chlorogenic acid from spectacular honeysuckle with ultrasonic wave was studied.On the basis of mono factor and orthogonal experimental design,the influence of several parameters on the extraction rate of chlorogenic acid was investigated,including ultrasonic time,material/extraction solution ratio,ethanol concentration,extraction temperature.The optimal extraction process was determined.The result shows that the optimum extraction conditions extracting of chlorogenic acid from spectacular honeysuckle by ultrasound were as follows:ethanol concentration 60%,extraction temperature 70 ℃,ultrasonic time 40 min and ratio of liquor to material 20 mL/g.Under the above optimum conditions,the chlorogenic acid extracted from spectacular honeysuckle was yielded by 36.72 mg/g.