Biocompatible Membranes with Special Functions for Biosensor's Application.

Biocompatibility is indispensable to biosensors for in vivo purpose. To those for in vitro applications biocompatibility can also promote their stability and life time. 2-Methacryloyloxyethyl phosphorylcholine, abbreviated as MPC, is an inert biocompatible material. Biocompatible membranes with special functions including diffusion-limiting effect, selective permeability, and the capability of immobilizing enzymes were obtainable by the copolymerization of MPC with other monomers. These membranes were applied to fabricate needle-type glucose sensors. The sensors were conferred with a wide workable range, good biocompatibility, remarkable long-term stability, and the ability of curtailing interfering responses upon application of these specially functionalized biocompatible membranes.