In order to investigate organophosphorus pesticide residue in vegetables,GC- MS was employed to determine the organophosphorus pesticide residues in more than 4000 vegetable samples gathered from pollution-free vegetable producing bases,open markets,supermarkets,wholesale markets and so on. The results showed the pesticide residue over standard rate decreased from 8. 51% to 1. 12% during 2006 and 2012,which was on a declining curve,indicating a pesticide residue was improved year by year. The relevance ratio and pesticide residue over standard in vegetables were on a declining curve; and the kinds of pesticide transferred from high- toxic pesticide,forbidden pesticides to low- toxic pesticides,such as Dursban,triazophos; The over standard rate saw a most highest in cabbages and green-leave-vegetables,the pesticide over standard rate in tegume vegetables and melon vegetables were lower. Preliminary analysis of the current situation of pesticide residue in vegetables in Guizhou province was made,and relevant proposes was arose.