Propofol target controlled infusion on bis pectral guided sedation assisted intravertebral anesthesia for laparoscopic operation

Objective To investigate the feasibility and superiority of propofol target controlled infusion on bispectral guided sedation assisted intravertebral anesthesia for laparoscopic operation. Methods Sixty cases undergoing laparoscopic operation were randomly divided into group A (n = 30) and group B (n = 30).Patients in two groups were all taken combined-spinal epidural anesthesia and the analgesia planes were controlled at between T6 and T8 .Two groups were administrated 1 μg/kg(10 μg/ml) fentanyl before injected propofol.In group A,propofol was target controlled infusion on bispectral guided;in group B,propofol was injected load quantity followed by sustaining intravenous injection. The changes of vital signs at before and end anesthesia were monitored in each group.The total dose of propofol,operation time,the time of postoperative recovery,the volume of infusion and incidence of adverse reaction were compared between the two groups.Results Compared with group B,the vital signs of group A is stablen,adverse reaction was less; the total dose of propofol significantly decreased;the time of postoperative recovery was significantly fasten ( P 0.05). Conclusion Propofol target controlled infusion on bispectral guided sedation assisted intravertebral anesthesia for la-paroscopic operation has satisfying and safe anesthetic effects,which can regulate depth of anesthesia exact,decrease dosage of propofol and adverse reaction.