In this article,the influence of water-stress on germination and growth of seedlings in wheat(Triticum aestivum L.) were studied.Wheat were planted in plastic pots in a greenhouse under different water content of soil,including 9%,12%,15%,18%,21% and 24%.Germination rate and content of H_2O_2,MDA and chlorophyll were measured.Also,enzymatic antioxidants such as SOD,POD,CAT which clean AOS,existed in plant cells,were studied.The results showed that germination rate and chlorophyll content decreased,while H_2O_2 and MDA content increased with the increasing of water content of soil.SOD and POD activities raised and CAT activities had no significantly change under slightly drought-stress,but it was decreased under severe stress.These results suggested that the system of defense enzymes might play a key role by balancing all of the responding enzymes under drought condition in plants.