整合酶
转座酶
转座因子
遗传学
生物
换位(逻辑)
DNA
计算生物学
整合酶
Tn3转座子
功能(生物学)
基因组
基因
计算机科学
人工智能
作者
Laurence Haren,Bao Ton‐Hoang,Michaël Chandler
出处
期刊:Annual Review of Microbiology
[Annual Reviews]
日期:1999-10-01
卷期号:53 (1): 245-281
被引量:240
标识
DOI:10.1146/annurev.micro.53.1.245
摘要
Transposable elements appear quite disparate in their organization and in the types of genetic rearrangements they promote. In spite of this diversity, retroviruses and many transposons of both prokaryotes and eukaryotes show clear similarities in the chemical reactions involved in their transposition. This is reflected in the enzymes, integrases and transposases, that catalyze these reactions and that are essential for the mobility of the elements. In this chapter, we examine the structure-function relationships between these enzymes and the different ways in which the individual steps are assembled to produce a complete transposition cycle.
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