硫嘌呤甲基转移酶
炎症性肠病
硫唑嘌呤
医学
巯基嘌呤
溃疡性结肠炎
疾病
胃肠病学
克罗恩病
内科学
免疫学
重症监护医学
作者
Nanne K.H. de Boer,Laurent Peyrin‐Biroulet,Bindia Jharap,Jeremy Sanderson,Berrie Meijer,Imke Atreya,Murray L. Barclay,Jean–Frédéric Colombel,Anthony Lopez,Laurent Beaugerie,Anthony M. Marinaki,Adriaan A. van Bodegraven,Markus F. Neurath
标识
DOI:10.1093/ecco-jcc/jjx181
摘要
Thiopurines, available as azathioprine, mercaptopurine, and thioguanine, are immunomodulating agents primarily used to maintain corticosteroid-free remission in patients with inflammatory bowel disease. To provide a state-of-the-art overview of thiopurine treatment in inflammatory bowel disease, this clinical review critically summarises the available literature, as assessed by several experts in the field of thiopurine treatment and research in inflammatory bowel disease.
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