血清蛋白电泳
免疫固定
蛋白质凝胶电泳
多发性骨髓瘤
电泳
骨髓瘤蛋白
化学
医学
色谱法
聚丙烯酰胺凝胶电泳
内科学
免疫学
抗体
生物化学
单克隆
酶
单克隆抗体
作者
Shanshan Zhu,Wei Li,Meilin Lin,Tiemin Li
出处
期刊:JCPSP. Journal of the College of Physicians & Surgeons Pakistan
[College of Physicians and Surgeons Pakistan]
日期:2021-07-01
卷期号:31 (07): 864-867
被引量:5
标识
DOI:10.29271/jcpsp.2021.07.864
摘要
The objective of this study was to investigate the diagnostic significance of serum protein electrophoresis and immunofixation electrophoresis detection in diagnosis of multiple myeloma (MM).One hundred and five patients were investigated.The detection rate of M protein by immunofixation electrophoresis detection was better (105 cases, 100%) than that of serum protein electrophoresis (101 cases, 96.19%, p<0.001).The M band was not detected by serum protein electrophoresis in four cases (3.81%), among which one case (0.95%) was identified as IgA type and 3 cases (2.86%) as light chain type after immunoglobulin analysis.Immunofixation electrophoresis detection technique can be used for screening M protein in patients with atypical MM; and immunofixation electrophoresis detection technique can increase the diagnosis accuracy in patients with atypical MM.
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