Nickel‐Catalyzed, Reductive C(sp3)−Si Cross‐Coupling of α‐Cyano Alkyl Electrophiles and Chlorosilanes

Abstract A nickel/zinc‐catalyzed cross‐electrophile coupling of alkyl electrophiles activated by an α‐cyano group and chlorosilanes is reported. Elemental zinc is the stoichiometric reductant in this reductive coupling process. By this, a C(sp 3 )−Si bond can be formed starting from two electrophilic reactants whereas previous methods rely on the combination of carbon nucleophiles and silicon electrophiles or vice versa.