医学
前列腺癌
肿瘤科
前列腺
癌症研究
阉割
内科学
癌症
激素
作者
Oliver Sartor,Johann S. de Bono,Kim N.,Karim Fizazi,Ken Herrmann,Kambiz Rahbar,Scott T. Tagawa,Luke T. Nordquist,Neil Vaishampayan,Ghassan El‐Haddad,Chandler H. Park,Tomasz M. Beer,Alison A. Armour,Wendy J Pérez-Contreras,Michelle DeSilvio,Euloge Kpamegan,Germo Gericke,Richard A. Messmann,Michael J. Morris,Bernd J. Krause
标识
DOI：10.1056/nejmoa2107322
摘要
Metastatic castration-resistant prostate cancer remains fatal despite recent advances. Prostate-specific membrane antigen (PSMA) is highly expressed in metastatic castration-resistant prostate cancer. Lutetium-177 (177Lu)–PSMA-617 is a radioligand therapy that delivers beta-particle radiation to PSMA-expressing cells and the surrounding microenvironment.
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