Progress on Vaccine Adjuvant CpG ODN

Synthetic oligodeoxynucleotides(ODN) containing unmethylated CpG motifs mimic the immunostimulatory activity of bacterial DNA.CpG ODN directly stimulate a variety of immunological effects.CpG ODN is used as vaccine adjuvants,where they increase the vaccine-specific immune responses and the mucosal immune responses.Ongoing clinical studies indicate that CpG ODN are safe and well-tolerated when administered as adjuvants to animals.