Effect of Chinese nutgall extracts on the expression of monocyte CD14 induced by lipopolysaccharide (LPS) of porphyromonas gingivalis (Pg)

AIM:To observe the effects of extracts of Chinese Nutgalls on the expression of monocyte CD14 induced by lipopolysaccharide (LPS) of Porphyromonas gingivalis(Pg).METHODS:Monocyte obtained by separating human blood cells was stimulated with LPS at the concentration of 25 μg/mL.Flow cytometry (FCM) was used to examine the effect of extracts from Chinese Nutgalls on the expression of monocyte CD14.RESUTLS:After administration with extracts from Chinese Nutgalls,expression of monocyte CD14 significantly decreased from 69.9±2.3% to 45.9%±3.7%.CONCLUSION:Extracts from Chinese Nutgalls can inhibit the expression of monocyte CD14,thus suggesting the anti-inflammatory effect of Chinese Nutgalls to treat and prevent periodontal diseases.