Comparison of Efficacy and Safety of Blood Specimen Collection via Radial Artery and Femoral Vein Puncture in Neonates

Objective To compare the efficacy and safety of blood specimen collection of neonates via radial artery and femoral vein puncture.Methods From March 2010 to February 2012,one hundred and eighty neonates were performed with blood specimen collection,and randomly divided into radial artery puncture group and femoral vein puncture group with 90 cases in each group.The success rate of one-time puncture,time of blood sampling,and incidence of adverse events associated with puncture(local damage) were compared between 2 groups.Results Comparing with femoral vein puncture group,a significantly higher success rate of one-time puncture(96.6% vs.85.6%,P 0.05) and shorter time of blood sampling[(4.10 ± 1.04) min vs.(6.4 ±1.21) min,P 0.01) ]were observed in radial artery puncture group.For radial artery puncture group,the local damage occurred in 7 cases,including 2 cases of hematoma,5 cases of bruising / petechiae.For femoral vein puncture group,local damage occurred in 34 cases,including 11 cases of hematoma,17 cases of bruising / petechiae,and 6 cases of red swelling.The incidence of adverse events associated with puncture in radial artery puncture blood group was significantly lower than that in femoral vein puncture group(7.8% vs.37.8%,P 0.01).Conclusion Neonatal radial artery puncture is a simple,effective and safe methods of blood sampling,which is worthy of clinical application.