Noradrenaline vs Terlipressin for Hepatorenal Syndrome (No To Hepatorenal Syndrome): A Meta-Analysis

Corresponding Author: Kenneth G. Samala, MD, UP-PGH, Manila, Philippines Email: kenn.samala@gmail.com Introduction: Hepatorenal syndrome (HRS) i s a functional renal impairment associated with advanced cirrhosis. The best treatment is liver transplantation; however, many patients die before this can be done. Terlipressin improves renal function in HRS, but recent studies have shown similar effects with the cheaper and more readily available norepinephrine. This review included randomized trials comparing noradrenaline to terlipressin for patients with type 1 HRS, as defined by the International Ascites Club.