Objective To establish the quality standard for the Sheshan Jiedu Powder.Methods Radix et Rhizoma Rhei,Radix Scutellaria,Cortex Phelloderdri Chinensis were identified by Pharmaeognistical identification,and Radix et Rhizoma Rhei was identified by physical and chemical method.Radix et Rhizoma Rhei,Cortex phellodendri chinensis were identified by TLC.The quality control of the Baicalin in Sheshan Jiedu Powder was used by HPLC.Results Radix et Rhizoma Rhei,Radix Scutellaria,Cortex Phellodendri Chinensis could be identified by Pharmaeognosty.Radix et Rhizoma Rhei could be identified by physical and chemical method Radix et Rhizoma Rhei,Corex Phellodendri Chinensis could be identified by TLC.The determination of Baicalin is not less than 15.0 mg/g.Conclusion The method is simple,aecurate,sensitive,reproducible and can be used for quantity control of the Sheshan Jiedu Powder.