Nonclinical Safety Pharmacology Studies Recommended for Support of First‐in‐Human Clinical Trials

This chapter contains sections titled: Introduction and Overview Timing of Safety Pharmacology Studies CNS Safety Pharmacology Cardiovascular Safety Pharmacology Respiratory System Safety Pharmacology Renal/Urinary Safety Pharmacology Gastrointestinal System Safety Pharmacology Autonomic Nervous System Safety Pharmacology Other Systems Discussion and Conclusions References