DNA-Programmed Tuning of the Growth and Enzyme-Like Activity of a Bimetallic Nanozyme and Its Biosensing Applications

双金属片 生物传感器 材料科学 纳米材料 纳米技术 抗坏血酸 纳米结构 合理设计 纳米颗粒 组合化学 化学 金属 食品科学 冶金
作者
Mengchao Cai,Yunqing Zhang,Zhongxu Cao,Lin Wang,Na Lü
出处
期刊:ACS Applied Materials & Interfaces [American Chemical Society]
卷期号:15 (15): 18620-18629 被引量:9
标识
DOI:10.1021/acsami.2c21854
摘要

Nanozymes, which combine the merits of both nanomaterials and natural enzymes, have aroused tremendous attention as new representatives of artificial enzyme mimics. However, it still remains to be a great challenge to rationally engineer the morphologies and surface properties of nanostructures that lead to the desired enzyme-like activities. Here, we report a DNA-programming seed-growth strategy to mediate the growth of platinum nanoparticles (PtNPs) on gold bipyramids (AuBPs) for the synthesis of a bimetallic nanozyme. We find that the preparation of a bimetallic nanozyme is in a sequence-dependent manner, and the encoding of a polyT sequence allows the successful formation of bimetallic nanohybrids with greatly enhanced peroxidase-like activity. We further observe that the morphologies and optical properties of T15-mediated Au/Pt nanostructures (Au/T15/Pt) change over the reaction time, and the nanozymatic activity can be tuned by controlling the experimental conditions. As a concept application, Au/T15/Pt nanozymes are used to establish a simple, sensitive, and selective colorimetric assay for the determination of ascorbic acid (AA), alkaline phosphatase (ALP), and the inhibitor sodium vanadate (Na3VO4), demonstrating excellent analytical performance. This work provides a new avenue for the rational design of bimetallic nanozymes for biosensing applications.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
2秒前
愤怒的稀发布了新的文献求助10
2秒前
3秒前
浮世繁华发布了新的文献求助30
4秒前
stride21完成签到 ,获得积分10
4秒前
123444发布了新的文献求助10
6秒前
赘婿应助夏宇采纳,获得10
7秒前
7秒前
大模型应助学术小张采纳,获得10
8秒前
依然小爽发布了新的文献求助10
8秒前
9秒前
youyou完成签到,获得积分10
11秒前
小商完成签到,获得积分10
12秒前
12秒前
leoling发布了新的文献求助30
12秒前
huco发布了新的文献求助20
13秒前
luopengdong发布了新的文献求助10
14秒前
Lily发布了新的文献求助10
17秒前
17秒前
kkkkk发布了新的文献求助500
18秒前
lovelife完成签到,获得积分10
18秒前
Summer_Xia完成签到,获得积分10
19秒前
时光完成签到,获得积分10
22秒前
like发布了新的文献求助10
23秒前
zj给Agee_Feng的求助进行了留言
23秒前
24秒前
25秒前
luopengdong完成签到,获得积分20
25秒前
cctv18应助苏素采纳,获得10
25秒前
27秒前
隐形曼青应助huco采纳,获得10
28秒前
kingripple发布了新的文献求助10
29秒前
xiaolaoshuboshi完成签到,获得积分10
29秒前
30秒前
愤怒的稀完成签到,获得积分10
33秒前
小奕完成签到,获得积分10
34秒前
海与星发布了新的文献求助10
35秒前
末岛发布了新的文献求助30
36秒前
海鲜完成签到,获得积分10
38秒前
小马甲应助Bellala采纳,获得10
39秒前
高分求助中
The three stars each : the Astrolabes and related texts 1070
Hieronymi Mercurialis de Arte Gymnastica Libri Sex: In Quibus Exercitationum Omnium Vetustarum Genera, Loca, Modi, Facultates, Et Quidquid Deniq. Ad ... Diligenter Explicatur (Classic Reprint) Paperback – 23 April 2018 1000
Manual of Clinical Microbiology, 4 Volume Set (ASM Books) 13th Edition 1000
Hieronymi Mercurialis Foroliviensis De arte gymnastica libri sex: In quibus exercitationum omnium vetustarum genera, loca, modi, facultates, & ... exercitationes pertinet diligenter explicatur Hardcover – 26 August 2016 900
De arte gymnastica. The art of gymnastics 600
Boris Pesce - Gli impiegati della Fiat dal 1955 al 1999 un percorso nella memoria 500
[Lambert-Eaton syndrome without calcium channel autoantibodies] 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 有机化学 工程类 生物化学 纳米技术 物理 内科学 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 电极 光电子学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 2403030
求助须知:如何正确求助?哪些是违规求助? 2102077
关于积分的说明 5302870
捐赠科研通 1829628
什么是DOI,文献DOI怎么找? 911818
版权声明 560421
科研通“疑难数据库(出版商)”最低求助积分说明 487448