Local metabolism in preclinical disease models studied with mass spectrometry imaging

Chapter 1 General introduction 13Chapter 2 Atheroma-specific lipids in ldlr -/-and apoe -/-mice using 2D and 3D matrixassisted laser desorption/ionization mass spectrometry imaging 41 Chapter 3 Metabolic alterations of atherosclerosis in LDLR-deficient mice using matrixassisted laser desorption/ionization mass spectrometry imaging 55 Chapter 4 Abdominal fascial healing in the first postoperative week: a MALDI-TOF mass spectrometry imaging to investigate lipids in rats 71 Chapter 5 Mass spectrometry imaging of L-[ring-13 C6]-labelled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma 83 Chapter 6 Impact