Detecting Local Myocardial Spatiotemporal Repolarization Gradients With Clinical Mapping Arrays

Repol^Loc has higher sensitivity to local spatiotemporal repolarization heterogeneities and alternans than traditional ARI. Although ARI only correlates with uniformly distributed changes in repolarization in the entire myocardium, Repol^Loc also provided accurate regional gradient assessment and duration alternans of repolarization. These findings suggest ARI has significant far-field contamination and Repol^Loc may provide a better clinical mapping tool for spatiotemporal repolarization gradient mapping.