生物
布提亚科
基因组
蝎子
基因组学
系统基因组学
进化生物学
比较基因组学
节肢动物
染色体
顺序装配
基因
参考基因组
基因组计划
非编码DNA
系统发育学
计算生物学
遗传学
克莱德
生态学
转录组
基因表达
毒液
作者
Martha Bryant,Asher M. Coello,Adam M. Glendening,Samuel A. Hilliman,Carolina Jara,Samuel S. Pring,Aviel Rodriguez Rivera,Jennifer Santiago Membreño,Lisa M. Nigro,Nicole Pauloski,Matthew R. Graham,Teisha King,Elizabeth L. Jockusch,Rachel J. O’Neill,Jill L. Wegrzyn,Carlos E. Santibáñez‐López,Cynthia Webster
摘要
Abstract Over 400 million years old, scorpions represent an ancient group of arachnids and one of the first animals to adapt to life on land. Presently, the lack of available genomes within scorpions hinders research on their evolution. This study leverages ultra-long nanopore sequencing and Pore-C to generate the first chromosome level assembly and annotation for the desert hairy scorpion, Hadrurus arizonensis. The assembled genome is 2.23 Gb in size with an N50 of 280 Mb. Pore-C scaffolding re-oriented 99.6% of bases into nine chromosomes and BUSCO identified 998 (98.6%) complete arthropod single copy orthologs. Repetitive elements represent 54.69% of the assembled bases, including 872,874 (29.39%) LINE elements. A total of 18,996 protein-coding genes and 75,256 transcripts were predicted, and extracted protein sequences yielded a BUSCO score of 97.2%. This is the first genome assembled and annotated within the family Hadruridae, representing a crucial resource for closing gaps in genomic knowledge of scorpions, resolving arachnid phylogeny, and advancing studies in comparative and functional genomics.
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