化学
二羟基化
克
比例(比率)
过渡金属
二醇
有机化学
立体化学
组合化学
催化作用
对映选择合成
细菌
遗传学
量子力学
生物
物理
作者
Wei Wu,H. Tan,Zhihui Jiang,Ping Wang,Xiao Zhou,Lin Ye,Yi Ding,Ming‐Zhong Zhang
标识
DOI:10.1016/j.tetlet.2024.155018
摘要
An efficient one-pot direct dihydroxylation of alkenes has been achieved. This reaction proceeds under transition-metal-free conditions and in water solution, producing the corresponding 1,2-diols in good to excellent yields. The discovery of an optimal pH environment is identified as a key factor in the current system, which ensures the generality and good functional group compatibility of this reaction. Moreover, the gram-scale dihydroxylation of alkenes was demonstrated and without significant decrease of the yield of product, making this protocol very practical.
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