Effect of Jiuwei Jiangzhi tablet on intestinal peristalsis in mice

Abstract This study is to observe the effect of nine-flavor lipid-lowering tablet on the peristalsis of small intestine in mice. The effect of the nine-flavor lipid-lowering tablet on the small intestinal peristalsis of mice was studied by measuring the distance of the carbon powder in the small intestine of the mouse. 60 mice,18-22 g of body weight, and half of male and female, were randomly divided into 5 groups, nine-flavor lipid-lowering tablets, medium and low-dose groups, Sanjiu Weitai suspension and the same volume of physiological saline, and each day was administered once for 7 days, with a volume of 0.2 mL/10 g of body weight. The mice were fasted prior to dosing on Day 7 (water), and after the last dose of 30 min, the mice were given the carbon-end suspension 0.2 mL/10 g of body weight for 30 min after the last dose. After 20 min, the mice were sacrificed after the cervical dislocation of the cervical spine. The abdominal cavity was cut, and the small intestine of the small intestine was isolated and the total length of the small intestine was measured (cm). And the propulsion. Compared with the blank group, Jiuwei Jiangzhi tablet low dose group could significantly promote intestinal peristalsis in mice, positive group and Jiuwei Jiangzhi tablet high dose, middle dose group also significantly increased peristalsis in mice. Jiuwei Jiangzhi tablet can promote peristalsis in small intestine of mice.