RNA干扰
生物
抑制器
先天免疫系统
核糖核酸
RNA沉默
机制(生物学)
遗传学
细胞生物学
免疫系统
基因
认识论
哲学
作者
Valerie Betting,Ronald P. van Rij
标识
DOI:10.1016/j.tim.2020.05.018
摘要
RNA interference (RNAi) is a powerful host defense mechanism against viruses. As a counter-defense, many viruses encode suppressors of RNAi, which – in plants – has provoked counter-counter-defense strategies. Recently, a mechanism was proposed in Drosophila (Zhang et al.) wherein a long noncoding RNA senses a virus-encoded RNAi suppressor to activate an innate immune response. RNA interference (RNAi) is a powerful host defense mechanism against viruses. As a counter-defense, many viruses encode suppressors of RNAi, which – in plants – has provoked counter-counter-defense strategies. Recently, a mechanism was proposed in Drosophila (Zhang et al.) wherein a long noncoding RNA senses a virus-encoded RNAi suppressor to activate an innate immune response.
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