Research progress of vaginal radioactivity injury

Radiotherapy is an important treatment of cervical cancer, the treatment of locally advanced cervical cancer mainly depends on external beam radiotherapy and brachytherapy. However, in the process of the cervical cancer radiotherapy, the vagina has an ambivalent role in the treatment of cervical cancer, being as well a target organ (upper vagina) as an organ at risk. Vaginal radiation-induced injury will appear when it received high doses of radiation. And sexual dysfunction caused by radiation-induced injury has become an important problem cervical cancer survivor. In this article, recent vaginal dose and vaginal radiation injury-related studies have been summarized to unravel the pathophysiological changes, clinical symptoms, clinical diagnosis and treatment of vaginal radiation-induced injury. Key words: Radiation-induced injury; Research progress; Cervical neoplasmsyr/radiotherapy