纳米技术
材料科学
生物相容性
纳米颗粒
超分子化学
非共价相互作用
癌症治疗
癌症
医学
化学
有机化学
分子
氢键
内科学
冶金
作者
Wei Ge,Lei Wang,Jiayao Zhang,Changjin Ou,Weili Si,Wenjun Wang,Qingming Zhang,Xiaochen Dong
标识
DOI:10.1002/admi.202001602
摘要
Abstract Most therapeutic agents for cancer are currently suffering from the shortcomings of poor solubility, severe side effects, and multidrug resistance. Supramolecular self‐assembly (SSA) in nanomedicines is a promising way to overcome these obstacles due to the distinguished properties of noncovalent self‐assembly such as functional diversity, easy stimulus‐response, high biocompatibility, and biodegradability. Moreover, it is more potential to transform them from lab to clinic. In this review, based on lots of state‐of‐the‐art studies, a summary is presented about the recent advances in SSA for cancer treatment, with the introduction of noncovalent driving forces, classifications, design, and applications of multifunctional self‐assembled nanoparticles (SANPs). Finally, the prospects of SANPs on both developing drugs and clinical transformation are discussed.
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