生物
优生性
繁殖
大黄蜂
卵子发生
Notch信号通路
卵巢
女王(蝴蝶)
生殖系统
动物
种姓
细胞生物学
进化生物学
膜翅目
解剖
生态学
遗传学
卵母细胞
信号转导
传粉者
法学
花粉
胚胎
授粉
政治学
作者
Elizabeth J. Duncan,Otto Hyink,Peter K. Dearden
摘要
The hallmark of eusociality is the reproductive division of labour, in which one female caste reproduces, while reproduction is constrained in the subordinate caste. In adult worker honeybees (Apis mellifera) reproductive constraint is conditional: in the absence of the queen and brood, adult worker honeybees activate their ovaries and lay haploid male eggs. Here, we demonstrate that chemical inhibition of Notch signalling can overcome the repressive effect of queen pheromone and promote ovary activity in adult worker honeybees. We show that Notch signalling acts on the earliest stages of oogenesis and that the removal of the queen corresponds with a loss of Notch protein in the germarium. We conclude that the ancient and pleiotropic Notch signalling pathway has been co-opted into constraining reproduction in worker honeybees and we provide the first molecular mechanism directly linking ovary activity in adult worker bees with the presence of the queen.
科研通智能强力驱动
Strongly Powered by AbleSci AI