化学
三氟乙酸
氢氧化钙
氯化物
组合化学
药物化学
有机化学
作者
Wilfried Becker,Gernot A. Eller,W. Hölzer
出处
期刊:Synthesis
[Thieme Medical Publishers (Germany)]
日期:2005-07-20
卷期号:2005 (15): 2583-2589
被引量:4
标识
DOI:10.1055/s-2005-872078
摘要
A novel synthesis of substituted 6-phenylpyrano[2,3-c]pyrazol-4(1H)-ones via reaction of various 2-substituted or 2,5-disubstituted 2,4-dihydro-3H-pyrazol-3-ones with phenylpropynoyl chloride using calcium hydroxide in refluxing 1,4-dioxane is described. N-Unsubstituted representatives were obtained by treatment of 4-methoxybenzyl-protected congeners with trifluoroacetic acid.
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