Conjugation-Mediated Detoxification and Reactive Metabolite Risks in Microbial Degradation of a Cyano-Liquid Crystal Monomer

-transferases, and glutamine synthetase, potentially involved in these transformations. Most conjugates showed reduced predicted toxicity, whereas lipid-bound derivatives tended to exhibit higher predicted toxicity. These findings highlight the role of microbial phase II metabolism in cyano-LCM transformation and emphasize the importance of evaluating the environmental fate and potential risk of conjugated metabolites in future risk assessment and bioremediation strategies.