Synthesis and Sensorial Description of New Sulfur-Containing Odorants

Various sulfur-containing odorants, such as 2-thioalcanes, 3-aeetylthio-2-alkyl alkanals, and trialklylated 1,3,5-dithiazines were prepared by conventional, parallel, and split-mix synthesis approaches. 2-Heptanethiol, newly identified in bell peppers, and 3-acetylthio-2-methylpentanal showed relatively low odor thresholds of 10 and 5 µg/kg water, respectively. Several odorants were found to develop interesting notes, which are compatible with both savory and sweet flavors.