Perspectives in post-genomic nutrition research.

This chapter outlines the interplay of the rather static mammalian genome with its rapidly changing nutritional environment as one of the most attractive and interesting areas in post-genomic research. The molecular descriptors of metabolism are described. Current limitations of the technologies when applied to studies in humans are presented. The analysis tools and investigative methods such as expression arrays, proteome analysis and high-throughput metabolite profiling used to study the response of mammalian organisms to changes in their nutritional environment are discussed.