Serum‐Inert Tandem‐Locked Fluorescent Probe for Specific Imaging of Intratumoral Complement System

fluorescence is mainly localized at the tumor periphery, which, however, extends into the tumor interior after chemotherapy, probably due to enhanced complement activation induced by chemotherapy-mediated apoptosis. These findings provide new insights into intratumoral complement systems and underscore the potential of the optical probe for complement system research and clinical diagnostics.