生物结合
超分子化学
纳米技术
点击化学
化学
组合化学
药物发现
化学生物学
生化工程
计算机科学
有机化学
材料科学
工程类
分子
生物化学
出处
期刊:IntechOpen eBooks
[IntechOpen]
日期:2020-10-13
被引量:6
标识
DOI:10.5772/intechopen.92692
摘要
Among nitrogen-containing heterocyclic compounds, 1,2,3-triazoles are privileged structure motif and received a great deal of attention in academics and industry. Even though absent in nature, 1,2,3-triazoles have found broad applications in drug discovery, organic synthesis, polymer chemistry, supramolecular chemistry, bioconjugation, chemical biology, fluorescent imaging, and materials science. Therefore, the development of facile and straightforward methodology for the synthesis of 1,2,3-triazoles is of noteworthy interest. In this study, emphasis will be given to numerous synthetic approaches for the synthesis of 1,2,3-triazoles, especially the popular click chemistry approach. Furthermore, several biological activities of this promising heterocycle will also be discussed.
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