Features of the composition of microorganisms inhabiting the intestinal mucosa in patients with seborrheic dermatitis

Objective - to study the microbial composition of the intestinal mucosa in patients with seborrheic dermatitis. Materials and research methods. We examined 67 pa­tients with seborrheic dermatitis aged 18-57 years; the average age of the patients was 29.5 years. Patients with seborrheic dermatitis having been examined represented by 45 (67.2 %) men and 22 (32.8 %) women. Among the patients examined by us, in 37 (55.2 %) the pathological process was localized only on the skin of the scalp, and in 30 (44.8 %) the pathological process spread to other areas of the skin. The duration of the disease ranges from 1 year to 15 years. Assessment of the microbiological state of the mucous membrane of the large intestine was carried out according to standard bacteriological meth­ods for the study of feces. We also applied non-invasive methods for the specific diagnosis of Helicobacter pylori. Results and its discussion. A comprehensive exami­nation of 67 patients with seborrheic dermatitis made it possible to identify Helicobacter pylori in 48 (71.6 %). In the examined patients with seborrheic dermatitis, the number of Bifidobacterium spp., Enterocjccus spp. and E. coli - respectively in 19 (59.4 %), 20 (62.5 %) and 21 (65.7 %), and Lctobacterius spp. and Bacteroides spp. - in 29 (90.6 %) and 23 (71.9 %). Among the opportunistic microorganisms detected in the cultures of the patients examined by us it was found: Staphyloclccus spp. in 23 (71.8%), Staphylococcus aureus - in 8 (25%), Klebsiella spp. - in 4 (112.5%), Candida with an average log (CUE) within the permissible norm - in 19 (59.4%) and being in a concentration exceeding normal values - in 5 (15.6%) patients with seborrheic dermatitis we observed. Con­clusions. The revealed changes in the microbiosis of the intestinal mucosa in patients with seborrheic dermatitis in a certain way indicate the significance of the number of microorganisms in the development of the pathological position, which must be taken into account when exam­ining and planning treatment for patients with seborrheic dermatitis.