西妥昔单抗
吉非替尼
克隆形成试验
细胞周期
癌症研究
放射增敏剂
辐射敏感性
细胞凋亡
抗辐射性
细胞周期检查点
表皮生长因子受体
表皮生长因子受体抑制剂
结直肠癌
细胞生长
化学
癌症
医学
内科学
放射治疗
生物化学
作者
Cinzia Antognelli,Isabella Palumbo,Simonetta Piattoni,Monica Calzuola,Beatrice Del Papa,Vincenzo Nicola Talesa,Cynthia Aristei
标识
DOI:10.1080/09553002.2020.1820610
摘要
Our results show that AZD8931 increases IR efficacy in LoVo cells, suggesting that it works as a potent radiosensitizer, even more efficient than Gefitinib and Cetuximab, opening new pathways of investigation for further in vitro and in vivo studies aimed at confirming its potential to improve local radiotherapy in CRC.
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