CD38
CD28
免疫系统
白细胞介素2受体
CD3型
分子生物学
川地69
细胞培养
生物
T细胞
化学
免疫学
CD8型
细胞生物学
遗传学
干细胞
川地34
作者
Л. М. Селимова,Л Б Калнина,Д Н Носик
出处
期刊:PubMed
日期:2016-01-01
卷期号:61 (12): 822-825
标识
DOI:10.18821/0869-2084-2016-61-12-822-825
摘要
The article considers expression of markers of activation of neoplastic CD4+ T-lymphocytic transplantable cellular line M T-4, transformed by T-lymphotropic human virus type I. It is demonstrated that in cells are detected such external proteins as CD25+, CD28+, CD38+, CD62L+, CD69+, CD95+ and HLA-DR+. The maximal number of these components was detected in three days after transplantation of cells. These indices reached average level for markers CD25+, CD28+, CD38+, CD69+, CD95+ and HLA-DR+ - more than 90% and for CD62L+ - 48%. The obtained results and cultivation of cells indicate that cells MT-4 can be used as a convenient model for testing of activity of immune modulation preparations.
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