Exploring ACSL4/LPCAT3/ALOX15 and SLC7A11/GPX4/NFE2L2 as potential targets in ferroptosis-based cancer therapy

Future Medicinal ChemistryAhead of Print EditorialExploring ACSL4/LPCAT3/ALOX15 and SLC7A11/GPX4/NFE2L2 as potential targets in ferroptosis-based cancer therapyGaurav Gupta, Asif Ahmad Bhat, Ahsas Goyal, Neelam Singla, Saurabh Gupta, Sanjay Sharma, Shvetank Bhatt & Kamal DuaGaurav Gupta *Author for correspondence: E-mail Address: gauravpharma25@gmail.comhttps://orcid.org/0000-0001-7941-0229School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Mahal Road, Jaipur, IndiaGlobal Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Science, Chennai, IndiaSearch for more papers by this author, Asif Ahmad Bhat https://orcid.org/0000-0003-4346-8319School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Mahal Road, Jaipur, IndiaSearch for more papers by this author, Ahsas Goyal https://orcid.org/0000-0003-0110-9238Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, IndiaSearch for more papers by this author, Neelam Singla https://orcid.org/0000-0002-3583-7025School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Mahal Road, Jaipur, IndiaSearch for more papers by this author, Saurabh Gupta https://orcid.org/0000-0001-6978-4243Department of Pharmacology, Chameli Devi Institute of Pharmacy, Khandwa Road, Village Umrikheda, Near Toll Booth, Indore, Madhya Pradesh, 452020, IndiaSearch for more papers by this author, Sanjay Sharma https://orcid.org/0000-0002-9328-0974Shri Vile Parle Kelavani Mandal's Narsee Monjee Institute of Management Studies, Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, Vile Parle West, Mumbai, Maharashtra, IndiaSearch for more papers by this author, Shvetank Bhatt https://orcid.org/0000-0001-8696-3462School of Health Sciences and Technology, Dr. Vishwanath Karad MIT World Peace University, Pune-411038, Maharashtra, IndiaSearch for more papers by this author & Kamal Dua https://orcid.org/0000-0002-7507-1159Discipline of Pharmacy, Graduate School of Health, University of Technology, Sydney, New South Wales, 2007, AustraliaFaculty of Health, Australian Research Center in Complementary & Integrative Medicine, University of Technology, Sydney, New South Wales, 2007, AustraliaSearch for more papers by this authorPublished Online:28 Jul 2023https://doi.org/10.4155/fmc-2023-0125AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: antioxidantscancerdrug therapyferroptosisreactive oxygen speciesReferences1. 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Oncol. 12(1), 34 (2019).Crossref, Medline, Google ScholarFiguresReferencesRelatedDetails Ahead of Print STAY CONNECTED Metrics Downloaded 26 times History Received 6 May 2023 Accepted 19 May 2023 Published online 28 July 2023 Information© 2023 Newlands PressKeywordsantioxidantscancerdrug therapyferroptosisreactive oxygen speciesFinancial & competing interests disclosureThe authorshave no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download