猪圆环病毒
生物
基因型
病毒学
圆环病毒
分子流行病学
流行病学
病毒
兽医学
基因
遗传学
医学
内科学
作者
Xugang Ku,Feng Chen,Panpan Li,Xuexiang Yu,Qi Sun,Feifei Xu,Ping Qian,Qiushui He
标识
DOI:10.1186/s12985-022-01893-0
摘要
Abstract Porcine circovirus 3 (PCV3) is a newly emerging virus and has been found associated with porcine dermatitis and nephropathy syndrome in pigs. Compared with PCV2, research into PCV3 cap gene sequencing is deficient. To investigate the prevalence and genotype distribution of PCV3, we collected 1291 samples from 211 pig farms throughout 15 provinces and municipalities. 312 out of 1291 samples were tested positive by PCR. We further sequenced and analyzed 164 PCR-positive samples. The majority (61.8%) of isolates we sequenced belong to genotype PCV3c. PCV3c is also the dominant genotype in Hubei, Hunan, Hebei province and Chongqing city. We found 3 sites under positive selection and located in predicted epitope peptide, revealing that the pig’s immunity may be a reason those sites are undergoing highly positive selection.
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