Unlocking the secrets of exercise: A pathway to enhanced insulin sensitivity and skeletal muscle health in type 2 diabetes

• Exercise impacts skeletal muscle and systemic metabolism, yet understanding the complex molecular mechanisms behind these effects remains a key research challenge. • Mapping the molecular effects of exercise with advanced “omics” can advance our understanding of muscle function and metabolism. • Exercise holds promise for managing and preventing type 2 diabetes, emphasizing the need for more research on individualized training and its molecular effects.