HAT lessons help hydrogen hop, skip, and jump

Nagib, RajanBabu, share a clever approach to remote desaturation triggered by metal-catalyzed hydrogen atom transfer (mHAT) to an alkene, followed by intramolecular 1,6-HAT, and terminated via mHAT. This method both realizes a valuable synthetic transformation and provides multiple lessons for the design of HAT-mediated reactions. Nagib, RajanBabu, share a clever approach to remote desaturation triggered by metal-catalyzed hydrogen atom transfer (mHAT) to an alkene, followed by intramolecular 1,6-HAT, and terminated via mHAT. This method both realizes a valuable synthetic transformation and provides multiple lessons for the design of HAT-mediated reactions.