Schiff bases, having amine group and their metal complexes are widely used for industrial purposes and also reveal a wide range of biological applications. This work describes the most promising biological activities. Cobalt metal complexes, the [Co(en) 3]2NO 3 has most potent inhibitory activity among three complexes , having 784.12 µg/ml IC 50 value while [Co(en) 3]2Cl shows mild inhibition i.e. 47.39±0.83 % .