持续性
连续流动
连续生产
过程(计算)
公制(单位)
批处理
生产(经济)
计算机科学
制造工程
工艺工程
生化工程
环境科学
工程类
运营管理
经济
环境工程
操作系统
生态学
宏观经济学
生物
程序设计语言
作者
Mark S. Kerr,Kevin P. Cole
标识
DOI:10.1016/j.crgsc.2022.100279
摘要
Continuous processing is now commonly used in the manufacturing of fine chemicals including agrochemicals and pharmaceuticals. Datasets are now available, including some on environmental sustainability aspects, that enable more direct comparison between related batch and flow processes. This article examines six continuous processes where an environmental sustainability concept or metric (e.g. process mass intensity) can be compared to that from a closely-related batch process in order to assess the impact that continuous manufacturing has on that theme. Some current case studies where additional Green Chemistry concepts are exemplified are shared along with how continuous processing impacts the manufacture. We illustrate situations where continuous processing can reasonably be expected to show sustainability advantages over batch, as well as a scenario where increased solvent usage in flow mode worsened the environmental profile. While we believe that continuous processing can provide sustainability benefits, there are cases where its application can have a negative effect on environmental metrics. Our hope is to provide impartial guidance for development and manufacturing scientists so they may best utilize continuous technologies in an environmentally responsible way.
科研通智能强力驱动
Strongly Powered by AbleSci AI