Effect of Certain Stabilizers on Photobleacing of Riboflavin Solutions

AbstractAbstractThe influence of certain stabilizers on the aerobic photobleaching of buffered riboflavin phosphate solutions exuosed to fluorescent light was investigated. Disodium ethylenediamine (EDTA) demonstrated the greatest stabilizing effect followed by thiourea, methyl paraben, DL-methionine and sodium thiosul fate. The photostabilizing effect of these agents increased as their concentrations increased. Other stabilizers enhanced the photostability of riboflavin solutions with lesser and varying degrees. The pH and buffer species of the solutions appared to infulence the rate of photodegradation of riboflavin solutions in the presence of absence of EDTA.