基因组
生物
步伐
口译(哲学)
遗传
人类基因组
德国的
遗传学
进化生物学
计算生物学
基因
计算机科学
历史
地理
考古
程序设计语言
大地测量学
作者
Ricardo Noguera-Solano,Rosaura Ruiz-Gutiérrez,Juan Manuel Rodríguez Caso
出处
期刊:Endeavour
[Elsevier]
日期:2013-12-01
卷期号:37 (4): 213-219
被引量:10
标识
DOI:10.1016/j.endeavour.2013.05.003
摘要
In 1920, the German botanist Hans Winkler coined the concept of the 'genome'. This paper explores the history of a concept that has developed in parallel with advances in biology and supports novel and powerful heuristic biological research in the 21st century. From a structural interpretation (the genome as the haploid number of chromosomes), it has changed to keep pace with technological progress and new interpretations of the material of heredity. In the first place, the 'genome' was extended to include all the material in the nucleus, then the sum of all genes, and (with the discovery of the structure of DNA) the sum of the nucleotide base sequences. In the early 21st century, it has become a much more complex and central concept that has spawned the growing field of studies referred to as the 'omics'.
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