DNA Damage Inhibitory Activities, Anti‐acetylcholinesterase, Anti‐procine α‐Amylase and Antioxidant Properties of Dolichos Lablab Bean

This underutilized variety of Dolichos lablab bean seed serves as a good source of natural antioxidants, which may be effective in reducing the risk of occurrence of certain diseases. This study was undertaken for the first time to address the limited knowledge regarding the, antioxidant activities, DNA damage inhibitory activity, bovine serum albumin (BSA) damage inhibitory activity, anti‐acetylcholinesterase, and anti‐porcine α–amylase in the lablab bean seed. The antioxidant capacity of lablab bean seeds were evaluated for their potential antioxidant activities using the ferric‐reducing/antioxidant power assay (FRAP), free radical‐scavenging activity (DPPH), nitric oxide (NO) radical‐scavenging assay, and 2,20‐azinobis(3‐ethylbenzothiazoline‐6‐sulfonic acid (ABTS). The lablab bean extract exhibited good antioxidant activity by effectively scavenging FRAP, DPPH, NO, and ABTS radicals. Additionally, excellent protective effects against BSA damage, as well as natural α‐amylase inhibitors were also shown. The bean extract had protective effects against DNA damage. The lablab bean may have a future role as an ingredient in the development of functional foods