Multicentral clinical trial of weitong granules for functional dyspepsia

Objective To investigate the efficacy and safety of weitong granules in treatment of functional dyspepsia. Methods The randomized controlled-multicenter and open clinical trails was conducted in 448 patients with functional dyspepsia. Group weitong granules and muxin shunqi Pills,group weitong granules and domperidone were using completely randomized, double-blind double-dummy controlled method (293 patients),open control group was using before and after of their own control method (155 patients).The treatment groups were administrated by double-blind double-dummy controlled numbers,and open group was administrated the on marked number of granules. The above groups were administrated one package one time with warm water,three times a day.Duration of treatment was seven days. Results The treatment group,control group and open group were similar of main symptoms of total effective rate.Markedly effective rate of treatment group,open group were better than control group(P0.01).The functional gastric emptying of total effective rate and markedly effective rate were no significant difference(P0.05). The traditional chinese medicine (TCM) syndrome of total effective rate and markedly effective rate, the treatment group and open group were better than control group(P0.05,P0.01). Conclusion The weitong granules for functional dyspepsia treatment is safe and good clinical efficacy.